The Kentucky Derby debuted in 1875, the horse race a vision of Meriwether Lewis Clark Jr., grandson of American explorer William Clark in hopes of reviving commonwealth's economy.
John Froelich, the oldest son of German immigrants, was born in Iowa in 1849. The grain mill operator tinkered away on a gasoline traction, the tractor, that changed global agriculture.
Abigail Adams proved a peerless patriot in the American Revolution with "a spirit that will not be conquered" while championing rights for women in the new nation.
Deborah Adler of New York has achieved acclaim in industry and art for her prescription bottle designs and labeling program that have helped to prevent thousands of deaths each year.
Captain John Parker, 46, was crippled by tuberculosis when he led 77 volunteers against 700 British regulars in the Battle of Lexington, igniting the American Revolution.
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